The maximum diameter of Pemetrexed formed during pd<50 μmpd<50 μm glass bead experiments was one millimeter, an enlargement factor (EF) of 20 relative to the initial grain size, while aggregates comprised of 40–70 μm beads achieved an EF of 40. Notably, the EF for the 150–210 μm pdpd fraction was approximately three; hence, the coarsest granulometry utilized in our experiments exhibited a limited capacity for aggregation, even at the highest NaCl concentrations. For the LS ash, much higher NaCl concentrations were necessary to achieve aggregation. The two ash fractions, fine and medium (pd<40 μmpd<40 μm, 40–90 μm40–90 μm), required a minimum NaCl concentration of 5000±150 mgkg−1 to aggregate with sufficient stability to survive the collection process. The large grained ash fraction (pd<300 μmpd<300 μm) barely aggregated and required high NaCl concentrations (20000±600 mgkg−1) to sediment as aggregates in the collection vessel. The EFs are 25 for fine, 35 for medium and 2 for coarse particles, respectively.
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