19鈥�21 Therefore, the findings from investigations of these parameters may reinforce routine monitoring of hypertensive patients in daily clinical practice to prevent CVD and other harmful consequences of hypertension.22 A large scale study conducted in Mexico showed that the most prevalent abnormality in Mexican urban adults, aged 20鈥�69 years, was HDL cholesterol below 0.9 mmol/L (46.2% for men and 28.7% for women). Hypertriglyceridemia
(>2.26 mmol/L) was the second most prevalent abnormality (24.3%). Increased LDL (鈮�4.21 mmol/L) was observed in 11.2% of the sample. Half of the hypertriglyceridemic subjects had a mixed dyslipidemia or low HDL cholesterol. More than 50% of the low HDL cases were not related to hypertriglyceridemia.23 The pan-European OTX015 chemical structure Survey of HDL measured lipids and other cardiovascular risk factors in 3,866 patients with type 2 diabetes and 4,436 nondiabetic patients undergoing treatment for dyslipidemia in eleven European countries, and showed that diabetic patients had lower HDL (1.22卤0.37 mmol/L
versus 1.35卤0.44 mmol/L, P<0.001) and higher TG (2.32卤2.10 mmol/L versus 1.85卤1.60 mmol/L, P<0.001) than nondiabetic patients.24 More diabetic compared to nondiabetic patients had low HDL (45% versus 30%, respectively), high TG (鈮�1.7 mmol/L; 57% versus 42%, respectively), or both (32% versus 19%, respectively). HDL <0.9 mmol/L was found in 18% of diabetic <a href="http://www.selleckchem.com/products/VX-765.html">VX-765 datasheet and 12% of nondiabetic subjects.24 Previous studies showed the high rate of CVD mortality among South-East Asian compared to the rest Bilirubin oxidase of the world and that majority of CVD deaths occur below the age of 70.25鈥�28 A wide range
of risk factors for CVD has been studied in Bangladesh, but few studies have measured the association of CVD risk with hypertension and lipid profile. A study in rural areas of Bangladesh reported that the prevalence of 鈥渉igh鈥� TC concentration (>240 mg/dL or >6.2 mmol/L) in Bangladesh is about 17%, 鈥渉igh鈥� LDL (鈮�160 mg/dL or 鈮�4.2 mmol/L) is about 2%, and 鈥渓ow鈥� HDL (<40 mg/dL or <1.04 mmol/L) is about 67%.29 Limitations Our study has several limitations. First, the sample size was obtained from an urban hospital and may not be representative of all hypertensive patients in Bangladesh. Second, our sample size was small, and the control group was selected purposively, not age and sex matched. In addition, we could not compare the effects of lipid profile variation due to diet, physical activity, medication, or other factors. Conclusion The results of this study demonstrate that patients with hypertension are more likely than normotensive patients to exhibit dyslipidemia, including elevated TC, LDL, TG, and reduced HDL cholesterol levels. Our results suggest that elevated BP may predict certain disturbances in lipoprotein metabolism. This association will help to develop future strategies for preventing both hypertension and dyslipidemia through proper lifestyle changes or medical management or by the combination of both.</div>
(>2.26 mmol/L) was the second most prevalent abnormality (24.3%). Increased LDL (鈮�4.21 mmol/L) was observed in 11.2% of the sample. Half of the hypertriglyceridemic subjects had a mixed dyslipidemia or low HDL cholesterol. More than 50% of the low HDL cases were not related to hypertriglyceridemia.23 The pan-European OTX015 chemical structure Survey of HDL measured lipids and other cardiovascular risk factors in 3,866 patients with type 2 diabetes and 4,436 nondiabetic patients undergoing treatment for dyslipidemia in eleven European countries, and showed that diabetic patients had lower HDL (1.22卤0.37 mmol/L
versus 1.35卤0.44 mmol/L, P<0.001) and higher TG (2.32卤2.10 mmol/L versus 1.85卤1.60 mmol/L, P<0.001) than nondiabetic patients.24 More diabetic compared to nondiabetic patients had low HDL (45% versus 30%, respectively), high TG (鈮�1.7 mmol/L; 57% versus 42%, respectively), or both (32% versus 19%, respectively). HDL <0.9 mmol/L was found in 18% of diabetic <a href="http://www.selleckchem.com/products/VX-765.html">VX-765 datasheet and 12% of nondiabetic subjects.24 Previous studies showed the high rate of CVD mortality among South-East Asian compared to the rest Bilirubin oxidase of the world and that majority of CVD deaths occur below the age of 70.25鈥�28 A wide range
of risk factors for CVD has been studied in Bangladesh, but few studies have measured the association of CVD risk with hypertension and lipid profile. A study in rural areas of Bangladesh reported that the prevalence of 鈥渉igh鈥� TC concentration (>240 mg/dL or >6.2 mmol/L) in Bangladesh is about 17%, 鈥渉igh鈥� LDL (鈮�160 mg/dL or 鈮�4.2 mmol/L) is about 2%, and 鈥渓ow鈥� HDL (<40 mg/dL or <1.04 mmol/L) is about 67%.29 Limitations Our study has several limitations. First, the sample size was obtained from an urban hospital and may not be representative of all hypertensive patients in Bangladesh. Second, our sample size was small, and the control group was selected purposively, not age and sex matched. In addition, we could not compare the effects of lipid profile variation due to diet, physical activity, medication, or other factors. Conclusion The results of this study demonstrate that patients with hypertension are more likely than normotensive patients to exhibit dyslipidemia, including elevated TC, LDL, TG, and reduced HDL cholesterol levels. Our results suggest that elevated BP may predict certain disturbances in lipoprotein metabolism. This association will help to develop future strategies for preventing both hypertension and dyslipidemia through proper lifestyle changes or medical management or by the combination of both.</div>