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Fig Fig Location of DHS clusters in and circles

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2. Data and methods
The 2007 DRC DHS tested 9275 individuals within 300 clusters for HIV. The 2013 DHS approximately doubled the data collection of 2007, testing 18,257 individuals within 536 clusters. For both surveys the split between female and male HIV testing is roughly even. Latitude/longitude coordinates are missing for seven clusters in the 2007 data and 44 clusters in the 2013 data; HIV testing data from those Tirapazamine clusters were not considered for further analysis.
To develop a sense of how the distribution may have changed from 2007 and 2013, we simply subtract the 2007 map from the 2013 map, making note that doing so only provides a visualization of change across space and time, and no formal way to assess change over space and time. We use this descriptive approach, as opposed to formally modeling a spatio-temporal process, because the surveys were largely conducted in different locations in 2007 and 2013, although some of the sampling locations were likely the same as in 2007. As a result, sodium-potassium pump was not clear how to fit a model to the data that appropriately captured the spatial and temporal correlation structure in the data.

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